| IAT Cargo Airlines | VGO | ||
| IBC Airways Inc | II | CSQ | 175 |
| Iberia | IB | IBE | 075 |
| Iberworld | IWD | ||
| Ibex Airlines | FW | IBX | |
| Icar Airlines | C3 | IPR | 655 |
| Icaro | X8 | 545 | |
| Iceland Express | JXX | ||
| Icelandair Cargo | FI | ICE | 108 |
| Ikaros Fly | IKR | ||
| Ilavia Airlines | ILV | ||
| ILPO Aruba Cargo | IO | ILP | |
| Imair Airline | IK | ITX | 166 |
| Impala Air | IPL | ||
| Imperial Airlines | REJ | ||
| Imperial Cargo Airlines | RCN | 765 | |
| Impulse Aero | IMR | ||
| Impulse Airlines | VQ | OAA | 253 |
| Imtrec Aviation | IMT | ||
| Independent Air Freighters | |||
| Indian Airlines | IC | IAC | 058 |
| Indian Ocean Airways | |||
| IndiGo Airlines | 6E | IGO | |
| Informtrans-Avia | INS | ||
| Intal Avia | INL | ||
| Inter Airlines | 6K | INX | |
| Inter Island Express | |||
| Inter Trans Air | ITT | ||
| Inter-Aviation Services | D6 | ILN | 625 |
| Inter-Canadian (Canadian Partner) | ICN | ||
| Interbrasil Star | Q9 | ITB | 151 |
| Intercontinental de Aviacion | RS | ICT | |
| Interflight | IFT | ||
| Interot Airways | IQ | IRT | 614 |
| Intersky | 3L | ISK | |
| Intersun Havacilik | IS | SWW | |
| Inversija | INV | ||
| Iran Air | IR | IRA | 096 |
| Iran Aseman Airlines | EP | IRC | 815 |
| Iraqi Airways | IA | IAW | 073 |
| Iron Dragon Fly | IDF | ||
| IRS Airlines | LVB | ||
| Island Air | WP | MKU | |
| Island Aviation Services | Q2 | DQA | |
| Islands Nationair | CN | 920 | |
| Islandsflug | HH | ICB | 652 |
| Islena Airlines | WC | ISV | 282 |
| Isles of Scilly Skybus | 5Y | IOS | |
| Israir | 6H | ISR | 818 |
| Istanbul Airlines | IL | IST | |
| Itali Airlines | 9X | ACL | |
| Itapemirim Transportes Aereos | K9 | ITM | 660 |
| Itek Air | GI | IKA | 420 |
| Ivan Air | IVN |